地佐辛不同給藥方式用于瑞芬太尼復(fù)合麻醉術(shù)后蘇醒期拔管及鎮(zhèn)痛鎮(zhèn)靜效果的影響分析
發(fā)布時間:2018-06-24 來源: 幽默笑話 點擊:
[摘要] 目的 探討地佐辛不同給藥方式用于瑞芬太尼復(fù)合麻醉術(shù)后蘇醒期拔管及鎮(zhèn)痛鎮(zhèn)靜效果的影響。方法 方便選取該院麻醉術(shù)后蘇醒期患者120例,選取時間為2015年1—10月,選擇隨機的方式對該院所有觀察對象進行分組(均采用瑞芬太尼復(fù)合麻醉),分為對照組-靜脈注射地佐辛,觀察組-肌肉注射地佐辛,每組患者60例,比較2組臨床指標(biāo)、不良反應(yīng)發(fā)生情況。結(jié)果 觀察組麻醉術(shù)后蘇醒期患者蘇醒時間(4.45±0.35)min、氣管拔管時間(8.22±1.35)min、鎮(zhèn)靜評分(3.34±1.86)分、鎮(zhèn)痛評分(2.21±0.25)分,顯著優(yōu)于對照組各項指標(biāo)(P<0.05)。觀察組麻醉術(shù)后蘇醒期患者不良反應(yīng)發(fā)生率1.67%,顯著低于對照組20.00%,2組間相比較差異有統(tǒng)計學(xué)意義(P<0.05)。結(jié)論 對麻醉術(shù)后蘇醒期患者采用肌肉注射地佐辛,能夠達到顯著的鎮(zhèn)痛鎮(zhèn)靜效果,同時還能有效降低其不良反應(yīng)發(fā)生率,值得研究。
[關(guān)鍵詞] 地佐辛;不同給藥方式;瑞芬太尼;蘇醒期拔管;鎮(zhèn)痛鎮(zhèn)靜
[中圖分類號] R614 [文獻標(biāo)識碼] A [文章編號] 1674-0742(2018)01(c)-0115-04
[Abstract] Objective This paper tries to observe the effect of different administrations of dezocine on tracheal extubation and analgesic sedation after remifentanil combined anesthesia. Methods A total of 120 patients were recruited during the recovery period of anesthesia in this hospital (from January to October 2015), all subjects were randomly divided into groups (remifentanil anesthesia was used), divided into control group - intravenous dezocine, observation group - intramuscular injection of dezocine, with 60 patients in each group, compared two groups of clinical indicators, the incidence of adverse reactions. Results The awakening time (4.45±0.35)min, tracheal extubation time(8.22±1.35)min, sedation score (3.34±1.86)points and analgesic score (2.21±0.25)points in the observation group, better than the control group(P<0.05). In the observation group, the incidence of adverse reactions was 1.67% in the awakening patients, which was significantly lower than that in the control group of 20.00%,the difference was stntistically significant(P<0.05). Conclusion Intravenous injection of dezocine in patients with recuperation after anesthesia can achieve significant analgesic and sedative effects, and can effectively reduce the incidence of adverse reactions, it is worth studying.
[Key words] Dezocine; Different modes of administration; Remifentanil; Recovery extubation; Analgesic sedation
瑞芬太尼在臨床上十分常見,常應(yīng)用于麻醉誘導(dǎo)中,具有較好的麻醉效果,但由于其麻醉后劑量依賴性躁動、痛覺過敏及疼痛等問題限制了該藥物的使用[1]。而地佐辛作為臨床上常用的鎮(zhèn)痛類藥物,研究認(rèn)為,在采用瑞芬太尼進行復(fù)合麻醉后給予其地佐辛進行干預(yù),能夠起到顯著的鎮(zhèn)靜和鎮(zhèn)痛效果,有效將上述問題進行解決[2-3]。因此,該研究對2015年1—10月收取的120例麻醉術(shù)后蘇醒期患者進行客觀的研究,并選擇一項合理麻醉方法,現(xiàn)報道如下。
1 資料與方法
1.1 一般資料
方便選擇該院麻醉術(shù)后蘇醒期患者,收取例數(shù) 120例,將120例患者進行分組,即觀察組、對照組這2組,每組60例。
納入標(biāo)準(zhǔn):①所有患者均符合手術(shù)適應(yīng)證;②患者無其他腹部疾病和腹部手術(shù)史;③所有患者均同意該次操作,并簽署知情同意書,經(jīng)該院倫理委員會批準(zhǔn);④臨床資料完整且依從性較高者。
排除標(biāo)準(zhǔn):①伴有凝血功能障礙者;②伴有感染性疾病者;③伴有心腦血管及其器質(zhì)性疾病者;④不同意該次研究,且依從性較差者;⑤臨床資料不完整者。
觀察組患者年齡在(44.35±1.65)歲,年齡范圍上限值:65歲,下限值23歲;男女性各占35/25例。
對照組患者年齡在(44.59±1.05)歲,年齡范圍上限值:65歲,下限值24歲;男女性各占36/24例。
相關(guān)熱詞搜索:芬太尼 鎮(zhèn)痛 術(shù)后 鎮(zhèn)靜 蘇醒
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