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        磁共振彌散張量成像在急性期彌漫性軸索損傷診斷中的應(yīng)用價值

        發(fā)布時間:2018-06-24 來源: 短文摘抄 點(diǎn)擊:


          [摘要] 目的 研究磁共振彌散張量成像(diffusion tensor imaging DTI)在診斷急性期彌漫性軸索損傷中的應(yīng)用價值。方法 方便篩選2016年1月—2017年1月南京醫(yī)科大學(xué)第一附屬醫(yī)院收治的彌漫型軸索損害急性期(DiffuseatonalinjuryDAI)患者50例作為研討目標(biāo),另挑選正常人員40名作為對照組。結(jié)果 ①急性期DAI患者胼胝體壓部FA值為(0.51±0.05),胼胝體膝部FA值(0.69±0.06),內(nèi)囊后肢FA值為(0.66±0.02)、大腦腳FA數(shù)值為(0.60±0.04),急性DAI患者的胼胝體壓部、膝部、內(nèi)囊后肢、大腦腳感興趣區(qū)的FA值與健康對照組對應(yīng)區(qū)域的FA值對比存在明顯區(qū)別,差異有統(tǒng)計(jì)學(xué)意義(P<0.05);但急性期DAI患者胼胝體體部、內(nèi)囊前肢FA目標(biāo)與健康對照組對應(yīng)區(qū)域的FA目標(biāo)對比無明顯區(qū)別,差異無統(tǒng)計(jì)學(xué)意義(P>0.05)。②急性期DAI患者胼胝體壓部RA值為(0.55±0.01),胼胝體體部RA值(0.60±0.03),內(nèi)囊后肢RA值為(0.50±0.05)、大腦腳RA數(shù)值為(0.49±0.03),急性DAI患者的胼胝體壓部、體部、內(nèi)囊后肢、大腦腳感興趣區(qū)的RA值與健康對照組對應(yīng)區(qū)域的RA值比較存在顯著區(qū)別,差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。③急性期DAI患者胼胝體壓部ADC值為(0.74±0.07),內(nèi)囊后肢ADC值為(0.66±0.03),急性期DAI患者胼胝體壓部、內(nèi)囊后肢ADC指標(biāo)與健康對照組對應(yīng)區(qū)域的ADC值比較存在顯著區(qū)別,差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論 對于急性期彌漫性軸索損害患者行DTI序列可見患者腦深部白質(zhì)纖維束FA、RA、ADC值明顯反常,據(jù)此剖析可知DTI依據(jù)患者腦深部各感興趣區(qū)域FA、RA、ADC數(shù)值判別急性彌漫性軸索損害患者的反常彌散性改動,能夠顯著提高DAI的檢出率與確診能力。
          [關(guān)鍵詞] 磁共振彌散張量成像;彌漫性軸索損傷;診斷
          [中圖分類號] R445 [文獻(xiàn)標(biāo)識碼] A [文章編號] 1674-0742(2018)01(c)-0003-04
          [Abstract] Objective This paper tries to evaluate the value of magnetic resonance diffusion tensor imaging in the diagnosis of diffuse axonal injury in acute phase. Methods 50 patients with diffuse axonal injury (Diffuse atonal injury DAI) in this hospital from January 2016 and January 2017 were conveient selected as the research objects, and 40 normal persons were selected as the control group. Results ①For acute DAI patients, the splenium FA value was(0.51±0.05), corpus callosum FA value (0.69±0.06), FA value of the posterior limb of the internal capsule(0.66±0.02), cerebral peduncle FA value(0.60±0.04), corpus callosum, genu and splenium posterior limb of internal capsule, cerebral peduncle region of interest FA value comparison has the obvious difference from the healthy control group of the corresponding region FA, with statistical difference(P<0.05); but in the acute phase of DAI patients of corpus callosum, anterior limb of the FA target and FA target group compared to healthy controls showed no significant difference between the corresponding region, without statistical significance(P>0.05). ②Acute DAI patients of splenium RA value was(0.55±0.01), corpus callosum RA value(0.60±0.03), RA value of the posterior limb of the internal capsule(0.50±0.05), cerebral peduncle RA numerical(0.49±0.03), corpus callosum splenium, body department, posterior limb of internal capsule, cerebral peduncle region of interest RA values compared with control group, there were significant differences, corresponding to the RA values of, with statistical significance(P<0.05). ③DAI patients with corpus callosum ADC value was(0.74±0.07), ADC value of the posterior limb of the internal capsule (0.66±0.03), DAI patients with corpus callosum, posterior limb of the internal capsule ADC index compared with control group there were significant differences, corresponding to the ADC values of, with statistical significance(P<0.05). Conclusion For acute stage patients with diffuse atonal injury patients DTI view visible deep brain white matter fiber tracts FA, RA, ADC values significantly abnormal, on the basis of the analysis on DTI each interested in the deep brain region of FA, RA, ADC value judging acute diffuse atonal injury patient’s abnormal diffuse changes, can clear progress clinical detection and diagnosis of diffuse atonal injury.

        相關(guān)熱詞搜索:張量 彌漫性 磁共振 彌散 成像

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